Rabbit anti‑Bacteria Cholera Toxin IgG Polyclonal RW-C56023-1

Antibody: Cholera Toxin Rabbit anti-Bacteria Polyclonal (HRP) Antibody, Application: WB, ELISA, Reactivity: Bacteria, Format: Horseradish Peroxidase, Unmodified, Descriptio: Cholera Toxin antibody RW-C56023 is an HRP-conjugated rabbit polyclonal antibody to bacteria Cholera Toxin. Validated for ELISA and WB., Targe: Bacteria Cholera Toxin, Hos: Rabbit, Reactivit: Bacteria (tested or 100% immunogen sequence identity), Clonalit: IgG Polyclonal, Conjugation: Horseradish Peroxidase, Purificatio: Purified, Modification: Unmodified, Immunoge: Purified Choleragenoid., Specificit: Recognizes the beta subunit of cholera toxin. The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP., Application: Western blot (1:20 - 1:200)
ELISA (1:200 - 1:1000), Usag: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested., Presentatio: PBS, 0.002% Thimerosal, 1% BSA, Storag: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate., Restriction: For research use only. Intended for use by laboratory professionals., Guarante: This antibody carries the RW 100% Guarantee.